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SwampNut

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SwampNut last won the day on July 6

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    XR650R, Zero SR/S

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    Phoenix, AZ

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  1. Cruises do seem to be incubators for new fun diseases. At least you didn't get hantavirus or whatever the fuck it was on that cruise a few weeks so. As far as I know, I've never had flu, but had RSV once. I do NOT recommend it.
  2. https://substance-over-noise.beehiiv.com/p/the-patient-barely-lost-weight-he-got-better-anyway A true miracle drug? Also this is specifically about Semaglutide, but probably applies equally to Tirzepatide and Retatrutide. Almost surely doesn't correlate with Cagrilintide or Eloralintide however. Clinical Takeaway Domain Key Finding Evidence Level Cardiovascular 20% MACE reduction (SELECT); benefit independent of weight loss FDA Approved Heart Failure (HFpEF) 38% reduction in CV death / worsening HF events (SUMMIT) Phase 3 RCT Chronic Kidney Disease (with T2D) 24% reduction in kidney composite; FLOW stopped early for benefit FDA Approved (T2D + CKD) Metabolic Liver Disease 63% vs 34% steatohepatitis resolution (ESSENCE) FDA Approved Obstructive Sleep Apnea ~20 fewer apnea events/hr vs placebo (SURMOUNT-OSA) FDA Approved Peripheral Artery Disease Significantly improved maximum walking distance (STRIDE) Phase 3 RCT Osteoarthritis −41.7 vs −27.5 WOMAC pain improvement (STEP 9) Phase 3 RCT Substance Use Disorders HR 0.64 for AUD hospitalization; real-world signal robust Observational + Small RCT Lean Mass / Muscle 20–40% of weight lost can be lean mass; exercise is the fix Emerging Concern
  3. Keep it? Get rid of it (if we can, don't know)?
  4. LOL, yes, and he doesn't.
  5. Or as we age, try getting OEM parts...
  6. I've been set on not modding the "new" XX I got, not sure how much is obsessive-like or not. I'm not sure what I'd do if I had to replace something like a fuel pump with an aftermarket part. I think for me, it's purely about looking OEM externally. I guess I've said exactly that. Also, still waiting for an OEM owner's manual WITH COVER so that I can truly complete it.
  7. https://archive.is/20260613153807/https://www.washingtonpost.com/health/2026/05/28/ozempic-may-be-reshaping-brain-scientists-say/ ...Melanie Cree at the University of Colorado Anschutz, is also running a GLP-1 trial in teens and young women with the condition, testing whether the drugs help by stabilizing weight and blood sugar. As part of that trial, her colleague Allison Shapiro scanned the participants' brains before and after. Within a few months, the connections in the region that helps direct attention had multiplied. "We didn't expect to see this effect, and we really don't know what it means," Shapiro said. ... That uncertainty has raised a larger question: Are the drugs acting directly on the brain, or are they reshaping the nervous system more indirectly by reducing inflammation, improving metabolism and easing stress on the body?
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  8. Another critical marker I forgot to note here. Long ago: A few years ago: Now: I've shared this in various places. I've actually been accused of faking this because it's "impossible" and then a few real idiots claim that plant based eating would make this worse.
  9. Fuck, I lost mine and really needed it this past weekend.
  10. Source? Brand? Or...how to find one? Clear lid never crossed my mind with heat and vacuum. Shit, that's why I ask here, didn't cross my mind. Obviously it can take any heat/vac I can dish out. Duh. Off to the thrift store.
  11. That's a great color for the surroundings.
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