In a ginormous new study, researchers found many health benefits of drugs like Ozempic and Mounjaro

[SwampNut]

Mildly annoying that these are now always referred to as "weight loss drugs" and not what they really we meant for; diabetes control.

 

https://futurism.com/neoscope/glp-1-ozempic-benefits-map?utm_source=tldrnewsletter

 

Looking at other disorders in the data ranging from Parkinson's disease and Alzheimer's to kidney disease and opiate addiction, Al-Aly and his team found that those who were on GLP-1 medications saw significant improvement across a staggering range of health concerns — and far beyond anything clearly linked to weight or blood sugar.

[DaveK]

Vaccines are bad, period.

 

 

[SwampNut]

LOL, ok, but vaccines and peptides...not related...  And the Venn diagram of anti-vaxxers and people on semaglutide for morbid obesity seems to overlap a lot.

 

[DaveK]

1 minute ago, SwampNut said:

LOL, ok, but vaccines and peptides...not related...  And the Venn diagram of anti-vaxxers and people on semaglutide for morbid obesity seems to overlap a lot.

 

 

I bet the general public, specifically those with not much education, obese, and dumb think they are vaccines.

[blackhawkxx]

How long before the patents are off and becomes affordable for the average person?

[Zero Knievel]

8 minutes ago, blackhawkxx said:

How long before the patents are off and becomes affordable for the average person?

 

Never if Big Pharma has anything to say about it.

[DaveK]

I'm with ZERO, never. 

 

[SwampNut]

1 hour ago, blackhawkxx said:

becomes affordable for the average person?

 

It already is, just don't buy it from big pharma.

 

1 hour ago, blackhawkxx said:

How long before the patents are off

 

20 years.  I am not actually sure what the legal details are with these peptides, because they are endogenous and easily made.  I kind of wonder if we will see these patents tested in court.

 

On top of that however, there are new versions of related peptides being made quickly now.  Semaglutide is old, though the patent was only issued a few years ago.  Tirzepatide is the hot new thing.  Now we have retatrutide which doesn't have the patent issued yet.  Each one improves on the other, so the real question is when will the older ones get cheap because everyone wants the new one?

 

1 hour ago, Zero Knievel said:

 

Never if Big Pharma has anything to say about it.

 

Luckily they don't.

 

[tomek]

Be careful. On the other hand proper nutrition and exercise are risk free. 

 

https://www.health.com/ozempic-vision-loss-naion-8764661 

 

 

 

[SwampNut]

It's even beneficial to your bank account, and global economy (unless you're a purveyor of junk, bad choices, and poison).

 

https://wildfirelabs.substack.com/p/the-100-trillion-disruption-the-unforeseen

 

For decades, the advertising model was simple: Trigger an emotional response, create an impulse, convert it into a purchase. This foundation supports the $400 billion global advertising industry.

What happens when those emotional triggers stop working?

Early consumer data on GLP-1s shows:

- 65% reduction in response to food advertising

- 40% lower click-through rates on impulse products

- 85% decrease in late-night online shopping

Madison Avenue is quietly panicking. One major agency (which asked not to be named) estimates that 50% of their current advertising strategies will be obsolete by 2027. They are right to worry.

 

 

 

Vegas has suddenly been dying off with record reduction in attendance, wonder if this is related?

 

Look at Las Vegas. Five major casinos are redesigning their floor plans, shrinking restaurant and bar space by 35% and expanding wellness spas and medical tourism facilities. Vegas, the city built on impulse spending, is investing in the post-impulse economy.

 

 

 

What hidden improvements will we see when people don't waste on processed junk, meat, and the like?  What boosts will go to their family wealth and other more worthy uses?

 

 

 

[blackhawkxx]

I noticed Weight Watchers commensals have shifted to talking about using WW with weight lose drugs.  

[SwampNut]

Ads becoming less effective is fantastic news.  If WW ads work before GLP-1s, then they should stop working after...LOL.

 

[jon haney]

Medical tourism??

WTF is that, beyond going to Mexico for a cheaper procedure that isn't covered by insurance?

[SwampNut]

1 hour ago, jon haney said:

Medical tourism??

WTF is that, beyond going to Mexico for a cheaper procedure that isn't covered by insurance?

 

That's exactly it, been a thing for a long time.  Wealthy Canadians come here to get things done that their "free" medical care won't do, or will take forever.  Americans go to Mexico, India, and other places for expensive procedures.  Really wealthy Americans fly to India to buy stolen kidneys, but just an average person can go there to get a $50k procedure done for $20k including the travel cost, and get a vacation.  Vegas can provide services for Canadians and Europeans to get things done here.  Even the Saudis will ship people here for work that isn't done right there.

 

When I lived in Tucson I went there for rx drugs and dental work.

 

 

[jon haney]

21 hours ago, SwampNut said:

 

That's exactly it, been a thing for a long time.  Wealthy Canadians come here to get things done that their "free" medical care won't do, or will take forever.  Americans go to Mexico, India, and other places for expensive procedures.  Really wealthy Americans fly to India to buy stolen kidneys, but just an average person can go there to get a $50k procedure done for $20k including the travel cost, and get a vacation.  Vegas can provide services for Canadians and Europeans to get things done here.  Even the Saudis will ship people here for work that isn't done right there.

 

When I lived in Tucson I went there for rx drugs and dental work.

 

 

Never heard it called tourism before.  I certainly wouldn't have called it that.

[SwampNut]

Interesting, what would you call it?

 

It's been a documented thing for a few thousand years starting in Greece and then Europe.  In the 18th century, spa/medical towns were popular, either because all the practitioners could gather and share, or because they thought places had magical healing.  Vegas could become our modern day spa town.

 

Tucson kind of is.  They have a lot of rehab and spa tourism.

[jon haney]

On 3/6/2025 at 12:46 PM, SwampNut said:

Interesting, what would you call it?

 

It's been a documented thing for a few thousand years starting in Greece and then Europe.  In the 18th century, spa/medical towns were popular, either because all the practitioners could gather and share, or because they thought places had magical healing.  Vegas could become our modern day spa town.

 

Tucson kind of is.  They have a lot of rehab and spa tourism.

Business trip?

I have never traveled far for what I would consider "medical reasons".  Just vacation or business.

Even then, I've only left the USA one time (Canada, 2003 I think).  Never owned a passport, yet.

[tomek]

Well, I own three passports. 🤪

[SwampNut]

2 hours ago, jon haney said:

Business trip?

I have never traveled far for what I would consider "medical reasons".  Just vacation or business.

Even then, I've only left the USA one time (Canada, 2003 I think).  Never owned a passport, yet.

 

So NOW who's the mainstream one and who's the weirdo?  LOL

 

We had a famous/infamous medical tourist here that "bought" a whole wing of a hospital for his wife for a week.  Some Saudi dude.  They even did physical construction to give them what they wanted (paid for).

 

If you google "dentist algodon travel" you'll get an entire list of medical travel agents and bookers with hotels and all sorts of things just geared around medical tourism to Algodon MX from Yuma.

[jon haney]

On 3/7/2025 at 3:39 PM, SwampNut said:

 

So NOW who's the mainstream one and who's the weirdo?  LOL

I'll own it this time, but that's extremely hard to tell with this bunch, and changes with every subject.

[SwampNut]

https://www.wsj.com/health/wellness/ozempic-weight-loss-drug-aging-health-benefits-d93a22f8

 

https://12ft.io/https://www.wsj.com/health/wellness/ozempic-weight-loss-drug-aging-health-benefits-d93a22f8

 

 

Key Points

What's This?

•  

  GLP-1s, including Ozempic, show promise in preventing age-related conditions like Alzheimer's, osteoarthritis and certain cancers.

•  

  GLP-1s work by suppressing appetite and reducing inflammation, potentially contributing to their preventive health benefits.

•  

  While promising, more robust studies are needed to confirm the causal effects of GLP-1s on longevity and healthspan.

 

 

Very low risk, and seemingly high benefit.

 

[blackhawkxx]

8 hours ago, SwampNut said:

Very low risk, and seemingly high benefit.

So if that's the case, are they suggesting everyone should be on it?

[DaveK]

On 3/6/2025 at 1:11 PM, jon haney said:

Never heard it called tourism before.  I certainly wouldn't have called it that.

 

I have friends that left the hotel business to start their own medical trip companies.  They vet the doctors, book the hotels, flights, care.....etc.  All one price.

 

My one buddy, Chris... just moved to Panama and bought a $9 million dollar yacht.  He was a stoner bellman with me back in the late 80's. 

[SwampNut]

5 hours ago, blackhawkxx said:

So if that's the case, are they suggesting everyone should be on it?

 

This isn't a smartass answer, but...

 

Who is "they" because some are leaning that way.

 

Because you still have to continue to weigh cost and benefit.  Cost meaning dollars, side effects, and potential risk.

 

Most people won't stick themselves with a needle without motivation, though studies show that needle phobia is WAY down because of Semaglutide.

 

We don't yet have a specific regimen and dose rate for general life sustainment.  Semaglutide has different protocols for diabetes vs weight loss.  Tirzepatide doesn't, but they still had to go through a process to decide that, and then still called it a different brand name.  Foibles, processes, (and justifiable) rules.

 

Edit to add:  Thanks to AI we are discovering an astronomical number of proteins suddenly and there are at least 20 but maybe 100 peptides related to this in testing now.  Peptide therapy is taking off hard, and we're just at the beginning.  Meeting up with a new subject tonight and mixing up a pen.

 

Oh, yeah, these are easy to make and easy to use, no visible needle.

 

 

[SwampNut]

https://www.vice.com/en/article/weight-loss-drugs-are-giving-men-ozempic-penis/

 

Weight Loss Drugs Are Giving Men ‘Ozempic Penis’

Already considered a miracle drug for its weight loss capabilities, men are now claiming that Ozempic has another notable use.