In theory, the effect of a 4 into 1 header could be duplicated and possibly exceeded by using the original pipes into a collector that was efficient at bottlenecking the flow. The mid-pipe needs to be roughly one and a half times the diameter of a single downtube. Smooth transition here means a lot. Megaphones rather than canisters make more power generally, but obviously don't quite match the aesthetic qualities of the CBR. The massive change in pressure wave as it reaches the canister is critical. This is a large optimization area to play with...

and a dyno or a personal dragstrip would be required.
A Power Commander obviously would be essential to getting the max out of any exhaust changes.
I doubt any of the fabrication and tuning would be worth the time and effort it would take to do it unless you just want to be able to say that you built your own exhaust.

Good on ya if that is your goal!

A new or used name brand 4into1 is cheap compared to that much work though.

Could you tell me where you are from
wynne? I'm curious because of your user name.